1607 – Jamestown, Virginia is settled as an English colony.
1787 – In Philadelphia, delegates convene a Constitutional Convention to write a new Constitution for the United States; George Washington presides.
1796 – Edward Jenner administers the first smallpox inoculation.
1804 – The Lewis and Clark Expedition departs from Camp Dubois and begins its historic journey by traveling up the Missouri River.
1836 – The Treaties of Velasco are signed in Velasco, Texas.
1863 – American Civil War: The Battle of Jackson takes place.
1897 – "The Stars and Stripes Forever" is first performed in public near Willow Grove Park, Philadelphia.
1913 – Governor of New York William Sulzer approves the charter for the Rockefeller Foundation, which begins operations with a $100 million donation from John D. Rockefeller.
1925 – Virginia Woolf's novel Mrs Dalloway is published.
1955 – Cold War: Eight Communist bloc countries, including the Soviet Union, sign a mutual defense treaty called the Warsaw Pact.
1961 – African-American Civil Rights Movement: The Freedom Riders bus is fire-bombed near Anniston, Alabama, and the civil rights protesters are beaten by an angry mob.
1973 – Skylab, the United States' first space station, is launched.
1988 – Carrollton bus collision: A drunk driver traveling the wrong way on Interstate 71 near Carrollton, Kentucky, United States hits a converted school bus carrying a church youth group. Twenty-seven die in the crash and ensuing fire.
1936 – Bobby Darin, American singer-songwriter and actor (d. 1973)
1944 – George Lucas, American director, producer, and screenwriter, founded Lucasfilm
1949 – Walter Day, American game designer and businessman, founded Twin Galaxies
1951 – Robert Zemeckis, American director, producer, and screenwriter
1959 – Robert Greene, American author and translator
1964 – Suzy Kolber, American sportscaster and producer
1984 – Mark Zuckerberg, American computer programmer and businessman, co-founded Facebook
1989 – Rob Gronkowski, American football player
1993 – Miranda Cosgrove, American actress and singer
1919 – Henry J. Heinz, American businessman, founded the H. J. Heinz Company (b. 1844)
1982 – Hugh Beaumont, American actor (b. 1909)
1987 – Rita Hayworth, American actress and dancer (b. 1918)
1993 – William Randolph Hearst, Jr., American journalist and publisher (b. 1908)
1997 – Harry Blackstone Jr., American magician and author (b. 1934)
1998 – Marjory Stoneman Douglas, American journalist and environmentalist (b. 1890)
1998 – Frank Sinatra, American singer and actor (b. 1915)
2003 – Robert Stack, American actor and producer (b. 1919)
2014 – Emanuel Raymond Lewis, American librarian and author (b. 1928)
2015 – B.B. King, American singer-songwriter, guitarist, and producer (b. 1925)
2015 – Stanton J. Peale, American astrophysicist and academic (b. 1937)
2015 – Franz Wright, Austrian-American poet and translator (b. 1953)
2016 – Darwyn Cooke, American comic book writer and artist (b. 1962)
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